![]() ![]() History and examĪL has been the principal applicant/co-applicant for a number of grants including: Engineering and Physical Sciences Research Council Research - Multiplexed AKI biomarker detection with a single molecule biosensor Leeds Cares - A novel, non-invasive diagnostic approach to assess kidney transplant health through the targeted measurement of biomarkers of kidney injury and immune response in kidney transplant recipients at the Leeds Teaching Hospitals NHS Trust Kidney Research Yorkshire - Use of enhanced technology to characterise haemodialysis treatment for acute kidney injury (AKI) Bringing It Home - Validation of a micro-sampling technique for measuring tacrolimus and creatinine remotely and to fund a research nurse British Renal Society - Renal function assessment with point of care creatinine in diverse populations (RAPID), and several NIHR grants including on a) Improving the quality of post-discharge care following AKI b) An investigation into the use of remote blood sample collection to reduce health inequalities in patients with mental health disorders c) A comparison of remote blood collection devices: a human factor use study d) Defining the characteristics for a novel automatic device to monitor urine output in catheterized patients e) Leeds Medtech and In-vitro Diagnostic Cooperative Grant Extension f) Surgical MedTech Co-operative for the 2019/20 proof-of-principle funding stream g) A pilot investigation into the use of beta-trace protein for residual renal function estimation in haemodialysis h) Application of functional MRI to improve assessment of chronic kidney disease (AFiRM study) i) SuperResPath-Renal: Quantitative super-resolution technology for a fast, decentralised clinical diagnosis of renal pathologies. Pyelonephritis in children is not covered in this topic. Pyelonephritis refers specifically to infections in the kidney. Urinary tract infection is a non-specific term that refers to infection anywhere in the urinary tract (the urethra, bladder, ureters, or kidneys). Complicated infections can result from underlying medical problems (e.g., diabetes mellitus, HIV), genitourinary anatomical abnormalities, obstruction (e.g., benign prostatic hypertrophy, calculi), and/or multi-drug-resistant pathogens, and are more likely in some patient groups (e.g., pregnant women, men). Most episodes are uncomplicated and are cured with no residual renal damage. Acute infections may be caused by enteric bacteria (e.g., Escherichia coli) that ascend from the lower urinary tract or that spread haematogenously to the kidney. ![]() Pyelonephritis, from the Greek 'pyelo' (pelvis), 'nephros' (kidney), and '-itis' (inflammation), describes a severe infectious inflammatory disease of the renal parenchyma, calices, and pelvis that can be acute, recurrent, or chronic. ![]()
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